We found no other significant relationships between pre-treatment MMP/TIMP concentrations (n = 30) and mortality, cranial nerve palsy, hemiparesis and paraparesis on admission by multivariate analysis, although there was a significant relationship between lower pre-treatment MMP-2 concentrations in CSF and hemiparesis (OR = 0, p = 0.02 [95% CI 0, 0.24]) on univariate analysis. This evidence concerns the gene TIMP1 and Paraparesis.