This conclusion is based on several lines of evidence: TAIII demonstrates the same selectivity towards breast cancer cell lines as BN108; TAIII induces apoptosis involving caspase-4 activation similar to BN108; TAIII induces transcriptional changes in breast cancer cells that largely overlap with these induced by BN108; both TAIII and BN108 inhibit mTORC1 in cancer cells and induce protective autophagy. Here, CASP4 is linked to cancer.