ADAMTS9 and type 2 diabetes mellitus: In the present study sample of Europeans, enriched in inherited susceptibility to type 2 diabetes, we show that the common diabetes-related C allele of rs4607103 at chromosome 3p14.3-2 upstream of ADAMTS9 is associated with a decrease in insulin sensitivity of peripheral tissues, as estimated from a euglycemic-hyperinsulinemic clamp.