In addition, strong inhibition of proliferation was observed in EOL1 cells (IC50 of 0.2±0.1 nM; Figures 5C), a hypereosinophilic tumour cell line expressing the FIP1L1-PDGFRα chimeric protein, which is associated with chronic eosinophilic leukaemia. The gene discussed is FIP1L1; the disease is neoplasm.