Indeed, enhanced IL-8 has been detected in blood and bronchial mucosa [11] and in bronchial epithelial cells of patients with asthma [12], in bronchoalveolar lavage fluid (BALF) of asthmatic and chronic bronchitis patients [13], in BALF and sputum from patients with COPD [14,15]. This evidence concerns the gene CXCL8 and chronic bronchitis.