While CXCL12 mRNA is expressed in pancreatic cancer tissues, CXCR4 mRNA is expressed both in pancreatic cancer tissues and in pancreatic cancer cell lines (AsPC-1, BxPC-3, CFPAC-1, HPAC and PANC-1) (Koshiba et al. 2000). The gene discussed is CXCR4; the disease is familial pancreatic carcinoma.