The mass-screened NB tumors contained LAPTM5-positive degenerating NB cells, nonetheless we could not detect a significant difference in the mRNA expression of this gene between favorable and unfavorable tumor samples, suggesting the up-regulation of LAPTM5 expression to be involved in the pro-death role in the late phase of PCD in regressing tumors and LAPTM5-positive degenerating NB cells are a small proportion in mass-screened NB tumors. Here, LAPTM5 is linked to neoplasm.