The statistical analysis, when carried out, compared tumor volume (> or < than 8.0cm3) with the variables in our study, which showed statistical significance when tumor volume was compared to lymph node involvement (pN+) (p = 0.029), tumor volume and p53 (p = 0.029) and tumor volume and p53+Ki-67 (p = 0.029). Here, MKI67 is linked to neoplasm.