MKI67 and neoplasm: As to tumoral staging, the cell proliferation marker was positive in 100% (10/10 cases) of the cases in which the neoplasia did not invade adjacent structures, that is, pT1, pT2 and pT3 and it was positive in 88.9% (16/18 cases) of the cases in which the neoplasia invaded adjacent structures (pT4); however this ratio Ki-67 versus pT, was not statistically significant, p = 0.523.