One study on a different cancer population (151 lung cancer cases and 172 hospital controls) by Michielis et al. [30] showed that the MLH3 (Leu844Pro) polymorphism was associated with an increased risk for lung cancer [OR: 1.97 (1.06-3.65 95% IC), p = 0.04]. This evidence concerns the gene MLH3 and lung carcinoma.