From testing a cohort of 57 SjS and 25 healthy control sera with a full-length La recombinant fusion protein, the geometric mean titer (GMT) of anti-La antibodies was 44,692 LU (95% CI, 28,604-69,827) for SjS sera, which was 4 times higher than the GMT of the control sera of 9,156 LU (95% CI, 8,097-10,355) (Figure 1). This evidence concerns the gene SSB and Schwartz-Jampel syndrome.