SCRIB and neoplasm: The benign tumour overgrowth was largely N-dependent, since expressing NACT alone (Figure 6I), or NACT with BskDN (Figure 6J), in eye disc clones also blocked differentiation and resulted in massively overgrown eye/antennal discs, albeit without the amorphous structure characteristic of the loss of cell polarity in the scrib- + NACT + BskDN clones.