Therefore results showed that eleven of the thirty HBV and HCV positive samples has elevated ALT, seven of them were markedly elevated (ALT ≥ 40 U/I) above the reference value (5-25 U/I) which indicate an acute infection, four were have mild ALT elevation (ALT = 28 to31 U/I) which indicate a chronic infection, whereas the remainder nineteen positive samples with normal ALT level which indicate a resolved infection. The gene discussed is GPT; the disease is infection.