Pkd1HA/ΔC and Pkd1Myc/ΔC pups were born at the expected mendelian ratio (Table 1), were viable and fertile and did not show any appreciable difference in renal, hepatic, or pancreatic cyst formation at 18 months of age as compared to Pkd1+/− mice (not shown). Here, PKD1 is linked to Pancreatic cysts.