PPARGC1B is located at 5q33, which has been previously linked to schizophrenia [44] and PPARGC1B participates in mitochondrial biogenesis and plays a role in fat oxidation and nonoxidative glucose metabolism [45], which is interesting in light of evidence of glucose metabolism abnormalities and mitochondrial dysfunction in schizophrenia. The gene discussed is PPARGC1B; the disease is schizophrenia.