The SNP rs10918270, located in the 15th intron of the gene ATF6 on chromosome 1, was identified under both additive and dominant modes of inheritance, but showed stronger association in the three sample meta-analysis under the dominant model (p = 7.5 × 10-6) with an average 2.3 year younger onset of PD. This evidence concerns the gene ATF6 and Parkinson disease.