Because in both N. brasiliensis and H. polygyrus infections, there is relative decline of the CD8αint subpopulation which express the highest levels of CD103 and CD205, it appears that the DC response in the MLN to gastrointestinal nematode parasites is dominated by an increase in resident lymphoid DC subpopulations, and not by increased recruitment of DC from the site of infection. This evidence concerns the gene LY75 and infection.