SIPA1 and metastatic malignant neoplasm in the lymph nodes: Furthermore, the other two SNPs of SIPA1 screened; rs931127 which is a 5' near gene SNP and rs746429 which is a synonymous (Ala (A) to Ala (A)) SNP, did not show significant association with breast cancer, yet were reported to be associated with lymph node metastasis in the previous study.