The AEs leading to discontinuation were increased ALT, lenticular opacities (classed as a serious AE), increased serum ferritin, cardiac failure in two patients (serious AEs), abdominal discomfort, hypotension (serious AE), dyspnoea (serious AE), gastrointestinal haemorrhage (serious AE) and marrow transplantation due to β-thalassaemia (serious AE). Here, GPT is linked to heart failure.