The genes ABCG4, ARNT2, BCOR, CABP2, CSTF2, DNTTIP1, FGG, IGF2BP1, MAL2, MMP11, RBM16, TM4SF1, ZBTB4, ZNF394 are involved in connective tissue disorders and inflammatory disease, which are prerequisite to TAA. The gene discussed is CABP2; the disease is connective tissue disorder.