The genes ABCG4, ARNT2, BCOR, CABP2, CSTF2, DNTTIP1, FGG, IGF2BP1, MAL2, MMP11, RBM16, TM4SF1, ZBTB4, ZNF394 are involved in connective tissue disorders and inflammatory disease, which are prerequisite to TAA. This evidence concerns the gene ZNF394 and connective tissue disorder.