PECAM1 and neoplasm: Finally, FACS analysis of tumors from non-transplanted RT2;VC mice revealed that some bona fide CD31+/LYVE-1+ TLEC express the myeloid marker CD11b (Figure S6), indicating that the integration of cells of the myeloid lineage into tumor lymphatics and their simultaneous expression of lymphatic endothelial cell markers occurs also in the absence of any bone marrow transplantation.