Waltzer mice are therefore models of DFNB12 nonsyndromic deafness and not USH1D even though at least 11 of the 12 mutant alleles of Cdh23 are hypothesized to be functional null alleles and are caused by nonsense (Cdh23v-3J, Cdh23v-5J, Cdh23v-6J), frameshift (Cdh23v, Cdh23v-J, Cdh23v-4J, Cdh23v-7J, Cdh23v-Alb), or splice site (Cdh23v-2J, Cdh23v-ngt, Cdh23v-bus) mutations [14-16]. The gene discussed is CDH23; the disease is nonsyndromic deafness.