Previously our laboratory had synthesized a novel copper chelate [Copper N-2(hydroxy acetophenon) glycinate (CuNG)] which was found to be a potent immunomodulator able to elevate the number of CD4+ IFN-γ producing cells in drug resistant tumor [Doxorubicin resistant Ehrlich Ascites Carcinoma (EAC/Dox)] bearing mice [20], [21]. The gene discussed is IFNG; the disease is neoplasm.