KRT8 and neoplasm: Similarly, compared with CK8-negative tumours, the proportion of CK8-positive cases was significantly higher among moderately poorly differentiated OSCCs (65.6% vs 94.1%, respectively, P<0.001), patients treated with NACT (46.4% vs 61.2%, respectively, P=0.0485), and large number (⩾4) of pathologically positive lymph nodes (25.6% vs 40.0%, respectively, P=0.0340).