Unfortunately, we could not perform a systematic analysis in paraffin-embedded benign or cancerous prostate cancer tissues from archival samples, as the commercial polyclonal antibody successfully used in western blotting with nuclear extracts (Figures 3 and 4) detected nucleolar dyskerin expression in a subset of normal uterine cervical cells, but only in very few prostate cancer cells, and the polyclonal antibody used on breast cancers (Montanaro et al, 2006) is depleted. The gene discussed is DKC1; the disease is prostate cancer.