In this study, a total of 54.93% of Chinese patients with hearing impairment showed evidence of genetic involvement either based on genetic screening or family history, and 18.31%, 13.73%, and 1.76% of the patients were determined to have inherited hearing impairment caused by GJB2, SLC26A4, and mtDNA 1555A>G mutations. Here, GJB2 is linked to Hearing impairment.