SOD1 and schizophrenia: Some previous, as well as, recent studies have pointed out protective roles of the antioxidant enzyme like superoxide dismutase (SOD) activity[27] and the antioxidant vitamins, namely ascorbate and alpha tocopherol under the oxidative stressful conditions found in schizophrenia.[19, 20] Hence, from the findings of our present study it can be suggested that administration of ascorbic acid and alpha tocopherol, particularly ascorbic acid might be helpful in reducing the oxidative stress induced damages in those schizophrenic patients who have to be treated by haloperidol for optimum benefit.