Known polymorphic alleles/regions from the TNF-α, LT-α, IL-1-α, IL-6, IL-10, TNFRI, TNFRII, IL-1R and IL-10R (detailed in Supplementary Table 1) were analysed in transplant patients with (n=45) or without (n=65) EBV-positive PTLD (designated PTLD and transplant control subject groups, respectively). The gene discussed is LTA; the disease is post-transplant lymphoproliferative disease.