Figure 1H shows a moderately dysplastic epithelial gland with fascin immunoreactivity in the cytoplasm but more intense than the mildly dysplastic adenoma shown in Figure 1G. Statistically across the sample group, the proportion of fascin-positive tumour epithelium and staining intensity correlated significantly (Table 2) with increasing dysplasia (mild, moderate or severe) exhibited by the adenoma (Figure 1G and H). This evidence concerns the gene FSCN1 and neoplasm.