FoxP3+ TIL infiltration of the tumour stroma at the primary site was of pronounced prognostic significance: patients with high stromal FoxP3+ TIL counts (>125.9 FoxP+ TIL/mm2) had a median survival time of 58 months while those with low FoxP3+ counts (<125.9 FoxP3+ TIL/mm2) had a median survival time of 32 months (hazard ratio = 0.23; C.I. 0.08 - 0.72; p = 0.006; Figure 3C and Table 3). Here, FOXP3 is linked to neoplasm.