We did not observe any significant differences in the relationship between 25(OH)D and ovarian cancer by season of blood collection, BMI (<25 versus ≥25 kg/m2), menopausal status at enrollment, VDR SNP genotype or haplotype, tumor stage (I-II versus III-IV), grade, or histological subtype (serous versus mucinous, clear cell, and endometriod) (data not shown). The gene discussed is VDR; the disease is ovarian cancer.