Chromatin immunoprecipitation (ChIP) analysis with a primer set covering the AP1 sites 1 and 2 confirmed the physical association of AP1 and YY1 with the endogenous miR-206 promoter in mouse hepatoma Hepa-1 cells by using specific c-Jun and YY1 antibodies (Figure 3d). The gene discussed is FOS; the disease is hepatocellular carcinoma.