All DRB1 genotypes associated with a lower predictive probability of T1D free survival than the population average contained the DR4 allele: DR3/DR4, DR4/DR4 DR4/DR8, DR4/DR6, DR4/DR7, DR1/DR4, and DR4/DR5. The gene discussed is HLA-DRB1; the disease is type 1 diabetes mellitus.