ARHGAP4 and chronic hepatitis: Six proteins out of 16 identified proteins including 5 above-mentioned proteins which were up-regulated in cirrhotic tissues (Cyclin-dependent kinase inhibitor p12, Cyclin-dependent kinase inhibitor 1, Antioxidant protein 2, Protein disulfide isomerase A2, C1-tetrahydrofolate synthase) and Rho-GTPase-activating protein 4 were up-regulated in chronic hepatitis tissues [see Additional file 1].