The mean percentage of memory B cells in RA patients did not change (26 ± 5% at baseline vs. 26 ± 9% at 12 weeks; data not shown); accordingly, absolute numbers of CD27+ B cells did not differ between baseline and 3 months post-treatment (11 ± 5 cells/μl vs. 6 ± 3 cells/μl). The gene discussed is CD27; the disease is rheumatoid arthritis.