MGP and glioblastoma: In addition, in silico analyses using the REMBRANDT database (http://rembrandt.nci.nih.gov, accessed 10th march 2009) revealed more than two-fold upregulation of MGP in glioblastomas as compared to non-neoplastic brain tissue, and a correlation (p = 0.0011) between MGP overexpression and worse survival in glioblastomas, suggesting that MGP overexpression is prognostically relevant.