VEGFA and neoplasm: Concerning these results, there is a possibility that angiogenic factors other than VEGF are relevant in the development of this neoplasm's vascularization, taking into account the fact that modulation of the angiopoietin family has been previously described in non-tumor models [38,39], as well as fibroblast growth factor [40], metalloprotease induction, and cellular adhesion-molecule expression [41].