NEUROG2 and Alzheimer disease: Taken together, we demonstrated that the expression levels of KIAA0125 and NEUROG2 were inversely regulated by an altered Aβ42/Aβ40 ratio: An increased Aβ42/Aβ40 ratio, which is typical of AD, up-regulated NEUROG2 but down-regulated KIAA0125, whereas the opposite regulation pattern was observed for a decreased ratio.