The observation of concordant expression of Gata-2, -3 and Fog-2 in the ganglia of neural crest origin (Tevosian et al, 1999; Tsarovina et al, 2004), migrating neural crest cells (Fog-2; Figure 3) and favourable neuroblastoma supports the hypothesis that developmental molecular pathways are intact in this subtype of neuroblastoma. The gene discussed is GATA2; the disease is neuroblastoma.