Figure 1 shows vascular (arrows) and tumor cell expression of PLXND1 in representative samples of brain metastasis of adenocarcinoma (A), glioblastoma multiforme (B), neuro-endocrine lung tumor (C), ovarian adenocarcinoma (D), and prostatic urothelial cell carcinoma (E). The gene discussed is PLXND1; the disease is neoplasm.