The overall agreement between T-SPOT.TB and TST excluding the patient with indeterminate IFN-γ result was 92.1% (47/51) (κ:0.754; se:0.11) and between QFN-G-IT and TST it was 98% (50/51) (κ:0.929; se:0.07). This evidence concerns the gene IFNG and tuberculosis.