One study reported that there was resolution of malignant ascites in 3 of 10 patients treated with intraperitoneal interferon alpha-2b.45 Another study showed a 36% complete response and 9% partial response with intraperitoneal administration of interferons in patients with ovarian cancer.46 The only significant frequently occurring side effect was pyrexia. This evidence concerns the gene IFNA2 and ovarian cancer.