By using in-house xMAP assays, we analyzed 8 EBV antibodies, including 5 IgA antibodies against VCA-gp125, p18, EA-D, EBNA1 or gp78 and 3 IgG antibodies to EA-D, EBNA1 or gp78, in a large scale of Cantonese healthy subjects and NPC patients. The gene discussed is COLQ; the disease is nasopharyngeal carcinoma.