APOE and supranuclear palsy, progressive, 1: Furthermore, comparison of network findings with other neurodegenerative diseases (e.g. Huntington's disease, PSP) and clinical/pathophysiological measures (e.g. (f)MRI, CSF, APOE status [38,39] or neuropsychological test-scores) would be of interest; it is conceivable that different cognitive symptoms arise from different types of network disturbance, or that neuronal or synaptic loss in discrete regions leads to specific network disturbance.