In our recent study using a cohort of high grade cancers, increased expression of MAO-A correlated with an increased percentage of Gleason grade 4 and 5 cancer in the largest (index) tumor and with pre-operative serum PSA levels [9], two powerful prognostic factors for recurrence of PCa after radical prostatectomy [3,10]. Here, KLK3 is linked to posterior cortical atrophy.