Table 4 shows the univariate and multivariate analysis of overall survival, age (P = 0.003), sex (P = 0.026), tumor size (P = 0.026), serum albumin level (P < 0.001), histology (P < 0.001), UICC stage (P < 0.001) and serum CEA level (P < 0.001) were significantly correlated to overall survival by univariate analysis. This evidence concerns the gene CEACAM5 and neoplasm.