When adjustments for several patho-physiological clusters of variables were carried out, the OR of CVD associated with apoB levels above 1.26 g/L did not change appreciably after controlling for non-lipid risk factors [BMI, smoking status, hypertension, DM] (OR, 2.3; 95% CI, 1.9 to 2.7), Lp(a) (OR, 2.3; 95% CI, 1.8 to 2.8) or markers of inflammation [CRP, leukocytes] (OR, 2.2; 95% CI, 1.8 to 2.6). The gene discussed is APOB; the disease is hypertensive disorder.