PLAT and coronary artery disorder: A combined analysis of studies evaluating t-PA in coronary diseases, adjusted for some risk factors, suggests that CHD risk is about 50% greater in those with increased levels: a comparison of those in the top third with those in the bottom third of baseline t-PA antigen values yielded an odds ratio for CHD of 2.20 (1.70 – 2.85; 21 = 36) after adjustment for age and town only, and of 1.48 (1.09 – 2.01; 21 = 6) after further adjustment for classical CHD risk factors.36,37