Synthesis of AFP is dramatically reduced in adulthood but can resume in case of liver pathologies (cirrhosis, hepatitis...) or of tumors such as hepatocellular carcinoma, germ cell tumors (embryonic carcinoma and teratocarcinoma) and some pancreatic and renal tumors (Masopust et al. 1968; Chiu et al. 1983; Abelev and Eraiser, 1999; Labdenne and Heikinheimo, 2002; Yuen and Lai, 2005; Ishigami et al. 2006). Here, AFP is linked to hepatocellular carcinoma.