In the studies described below, a screen for expression of 37 chemokines in prostate cancer cell lines and xenografts revealed high-level expression of CXCL16, an unusual chemokine that exists in both transmembrane and soluble forms [12], [13], and that can also function as a scavenger receptor for oxidized lipoprotein and bacteria [14]. The gene discussed is CXCL16; the disease is prostate carcinoma.