Obesity has been identified as a major risk factor for such cancer sites as colon, renal, breast, and endometrium (Bianchini et al, 2002; Calle and Kaaks, 2004; Rapp et al, 2005), whereas hypertriglyceridemia is relevant to obesity and insulin resistance (Despres and Lemieux, 2006). This evidence concerns the gene INS and obesity due to melanocortin 4 receptor deficiency.